More Than a Shortcut

From Serena Williams to Oprah Winfrey, a diverse group of public figures have openly discussed their use of GLP‑1 medications. Below, we break down who has used what, their results, and the bigger picture.

Which famous people have used GLP‑1?

A wide range of celebrities have admitted to using GLP‑1 drugs — some by name, others more generally. Here’s a quick reference:

Female celebrities who have openly shared their GLP‑1 journey

• • Serena Williams — lost 31 lbs in 8 months; focused on joint health.
• • Oprah Winfrey — holistic approach with hiking, strength training.
• • Amy Schumer — lost 50 lbs with Mounjaro; framed it as survival, not vanity.
• • Meghan Trainor — lost 60 lbs post‑pregnancy; emphasised feeling stronger.
• • Vanessa Williams — called Mounjaro a “game‑changer” for menopause weight.
• • Kelly Clarkson — reportedly used a GLP‑1; lost weight after a health scare.
• • Margaret Cho — helped curb binge‑eating impulses.
• • Dolores Catania — used GLP‑1 for thyroid and menopause weight.

Male celebrities who have openly shared their GLP‑1 journey

• • Elon Musk — tweeted about Wegovy and later Mounjaro; credited it for weight loss.
• • Andy Cohen — admitted to micro‑dosing a GLP‑1 to manage cravings.
• • Randy Jackson — has spoken about using GLP‑1 to manage diabetes and weight.
• • Anthony Anderson — shared his use of Mounjaro for type 2 diabetes and weight.

GLP‑1 celebrities: before & after

While individual results vary, here are reported weight changes for some of the most talked‑about celebrities. (Note: figures are based on public statements and may reflect different timeframes.)

1‑month comparisons

Early weight loss varies — some report 5–10 lbs in the first month, others see little change until higher doses. Here’s what’s been observed:

• • Oprah — reportedly lost ~10 lbs in the first month.
• • Serena — gradual loss, ~4‑5 lbs in first month.
• • Amy Schumer — rapid initial loss (~8‑10 lbs) due to higher starting weight and medical condition.
• • Elon Musk — shared that he lost ~5 lbs in the first few weeks.

Did Kelly Clarkson use GLP‑1 to lose weight?

Yes, multiple reports and interviews confirm that Kelly Clarkson used a GLP‑1 medication to lose weight after a health scare. She has been open about it, stating that her doctor recommended it after her bloodwork showed pre‑diabetic levels. She lost approximately 40 pounds, emphasising that she also changed her eating habits and started moving more.

How did Oprah lose weight so fast?

Oprah has credited her weight loss to a combination of a GLP‑1 medication, hiking, strength training, and mindful eating. She has been transparent about the drug’s role but stresses that she didn’t rely on it alone. Her approach is holistic and long‑term — she views the medication as a tool, not a magic bullet.

Which influencer admits to using GLP‑1?

Several influencers have come forward, including Remi Bader (who spoke about using Ozempic and later stopping due to side effects), Jackie O (Australian radio host), and Nikki Nettleton. Many have used their platforms to discuss both the benefits and the challenges of GLP‑1s.

Ozempic, Wegovy & Mounjaro celebrities

• • Ozempic celebrities: Elon Musk (also used Wegovy), Kelly Clarkson (reported), Remi Bader.
• • Wegovy celebrities: Elon Musk, Dolores Catania, Andy Cohen (micro‑dose).
• • Mounjaro celebrities: Amy Schumer, Vanessa Williams, Anthony Anderson.